Plasma cell mastitis should not be confused with breast cancer

 



 

 

 

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Plasma cell mastitis is an aseptic inflammation of the breast tissue. Because the inflammatory cells are mainly plasma cells, it is called plasma cell mastitis. The disease usually occurs in women who are 30 to 40 years old who have not been breastfeeding or who are pregnant or who are at or near menopause.

Plasma cell mastitis is mainly due to various reasons caused by fatty secretions stagnating in the breast ducts, leading to blockage of the breast ducts, and then the accumulation in the ducts stimulates the duct wall, causing the epithelium of the duct wall to fall off, resulting in accumulation in the lumen Lipid spillage stimulates nearby glandular tissue to react, causing plasma cell infiltration and fibrous tissue proliferation.

Plasma cell mastitis is very similar to breast cancer due to obvious breast lumps, milk pain, nipple discharge, inverted nipple, and breast distension, so it is easy to be misdiagnosed and mistreated. According to medical literature, the probability of plasma cell mastitis being misdiagnosed as breast cancer is 16.5%~63%, and patients who have been mistakenly undergoing modified radical mastectomy and radical mastectomy are 5%~50%. This undoubtedly caused undue pain and injury to the patient. Therefore, it is important for patients to understand the characteristics of this disease to help doctors make a diagnosis. The specific methods are as follows:

1. The patient should give a detailed medical history for the doctor to analyze and diagnose. Plasma cell mastitis has obvious symptoms such as redness, swelling, heat and pain in the early stage of onset, while breast cancer generally has no obvious symptoms in the early stage.

2. Plasma cell mastitis has a short onset time and rapid development of the disease. Large lumps in the areola area can appear in 3 to 5 months, and most of the breast cancer lumps are located in the upper outer or inner upper area away from the nipple. Moreover, the disease progresses slowly and is difficult to detect in the early stage.

3. The mass of plasma cell mastitis is flat, mostly appearing within a radius of 3 cm with the nipple as the center. It does not invade the pleural fascia and is not fixed to the chest wall. Breast cancer often infiltrates the pleural fascia and chest muscles, and the mass is fixed on the chest wall and is not easily pushed.

4. The nipple discharge of plasma cell mastitis is mostly serous, yellow or creamy, and if nipple discharge occurs in breast cancer, the discharge is mostly bloody secretions.

5. Patients with plasma cell mastitis may have ipsilateral axillary lymph node enlargement in the early stage of the disease, while lymph node metastasis of breast cancer is rare in the early stage.

6. Plasma cell mastitis is treated with anti-anaerobic drugs and broad-spectrum antibiotics. It can be seen that the nipple discharge disappears and the mass shrinks. However, the treatment of breast cancer with this method is often ineffective.

7. When necessary, patients should actively cooperate with doctors for mammography, cytology and intraoperative quick-freezing pathological examination. This is a necessary means to reduce misdiagnosis and mistreatment.

Plasma cell mastitis is a benign breast lesion, and surgical treatment is an effective radical measure. For early patients, a wedge resection of the expanded breast duct with additional part of breast tissue can be done. Simple mastectomy is feasible for a small number of patients who are older, have large lumps, or have heavy adhesion between the lumps and the skin, and sinus formation. Incision and drainage can also be performed for severe infections and abscess formation.

In short, patients with plasma cell mastitis must not blindly request radical mastectomy or extended radical mastectomy for breast cancer without a pathological basis to avoid unnecessary damage.

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